Lysozyme also known as muramidase is an enzyme that breaks down the glycosidic bond in the peptidoglycan component of bacterial cell walls, leading to the loss of integrity of the cell membrane and cell death.


What are Peptidoglycans (PGNs)?

Peptidoglycans (PGNs) are an integral component of bacterial cell walls, and are considered to be conserved products of bacterial metabolism and activity within the gastrointestinal (GI) tract. They are intricate and composed of repeating N-acetylmuramic acid sequences, which are linked together by b-1-4 bonds with N-acetyl glucosamine.  Although there is a significant turnover of PGNs resulting from the natural recycling of bacterial cell wall fragments in the gut, it has been reported that PGNs may elicit a pro-inflammatory response in the host's GI tract.Peptidoglycan is the major component of gram-positive bacterial cell wall.


  • Improved live weight
  • Antibacterial effect
  • Improved FCR
  • Immune stimulating functions
  • Optimized gut health
  • Improved digestion and absorption of nutrients
  • Reduced pathogenic bacteria in the gastrointestinal tract
  • Increased gut efficiency
  • Alternative to growth promoting antibiotics




VemoZyme® LZ substantially increases live weight, improves the feed conversion ratio and better PEF (production efficiency factor).

Higher PEF = improved live weight gain and good survival rate = higher productivity = Improved profit margins


What does the production efficacy factor (PEF) tell us about the profitability of an integrated broiler producer?

The Production Efficacy Factor (PEF) is crucial for broiler producers as it measures various aspects of performance, such as terminal live weight, age, growth rate, livability, and feed conversion efficiency. Producers strive to maximize growth rates and bird management practices to achieve a higher PEF, resulting in better weight gain, favorable survival rates, and higher overall yield. This can lead to lower costs per unit due to the dilutive effect of higher volumes achieved.

In pigs, lysozyme added to feed improves gastrointestinal health, reduces potential pathogen shedding, and improves growth and feed efficiency. Therefore, lysozyme is a viable alternative to traditional subtherapeutic antibiotic use in swine production.

The lysozyme improves gastrointestinal health, metabolic profile and alters the gastrointestinal bacteria ecology of swine.




  • The primary structure of lysozyme is a single polypeptide containing 129 amino acids.
  • Operates at pH 5
  • Active against gram-positive bacteria such as Bacillus, Staphylococcus and Streptococcus.
  • Modulates the host immune response to infection.
  • Causes bacterial cell lysis via targeted hydrolysis of bacterial cell walls, which are critical for the resistance of bacteria to osmotic stress.
  • Lysozyme is part of the innate immune system.
  • Lysozyme is a naturally occurring enzyme found in bodily secretions such as tears, saliva, and milk.



VemoZyme® LZ is applied at a dose of 150 g per ton feed.